Assay Detail
Binding
CHEMBL1046622
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant rat ALDH activity in liver mitochondria
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Mitochondria |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Target
Aldehyde dehydrogenase, mitochondrial (CHEMBL2812) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Bis(dialkylaminethiocarbonyl)disulfides as potent and selective monoglyceride lipase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.60 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL571699 | — | — | 1 | 4.80 |
| CHEMBL964 | DISULFIRAM | 4.0 | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL571699 | — | IC50 | = | 15848.93 | nM | 4.80 |
| CHEMBL964 | DISULFIRAM | IC50 | = | 39810.72 | nM | 4.40 |