Assay Detail
Binding
CHEMBL1047007
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperature
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.66 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1686 | ALPHA-KETOGLUTARIC ACID | — | 1 | 5.77 |
| CHEMBL90852 | N-OXALYLGLYCINE | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1686 | ALPHA-KETOGLUTARIC ACID | Kd | = | 1700.0 | nM | 5.77 |
| CHEMBL90852 | N-OXALYLGLYCINE | Kd | = | 2800.0 | nM | 5.55 |