Assay Detail
Unclassified
CHEMBL1047876
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Selectivity index, EC50 for NHDF to EC50 for Plasmodium falciparum 3D7
41
Total Activities
41
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Unclassified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 41 | 4.30 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL565949 | — | — | 1 | 4.89 |
| CHEMBL576457 | — | — | 1 | 4.48 |
| CHEMBL567374 | — | — | 1 | 4.47 |
| CHEMBL568471 | — | — | 1 | 4.44 |
| CHEMBL579258 | — | — | 1 | 4.43 |
| CHEMBL568472 | — | — | 1 | 4.42 |
| CHEMBL584678 | — | — | 1 | 4.35 |
| CHEMBL577042 | — | — | 1 | 4.32 |
| CHEMBL578578 | — | — | 1 | 4.29 |
| CHEMBL568695 | — | — | 1 | 4.25 |
| CHEMBL568243 | — | — | 1 | 4.15 |
| CHEMBL583004 | — | — | 1 | 4.15 |
| CHEMBL577470 | — | — | 1 | 4.12 |
| CHEMBL567582 | — | — | 1 | 4.10 |
| CHEMBL567375 | — | — | 1 | 4.08 |
| CHEMBL576658 | — | — | 1 | 4.06 |
| CHEMBL568470 | — | — | 1 | 4.04 |
| CHEMBL568438 | — | — | 1 | - |
| CHEMBL584813 | — | — | 1 | - |
| CHEMBL578579 | — | — | 1 | - |
| CHEMBL565360 | — | — | 1 | - |
| CHEMBL584886 | — | — | 1 | - |
| CHEMBL585191 | — | — | 1 | - |
| CHEMBL579016 | — | — | 1 | - |
| CHEMBL577694 | — | — | 1 | - |
| CHEMBL565361 | — | — | 1 | - |
| CHEMBL578968 | — | — | 1 | - |
| CHEMBL579199 | — | — | 1 | - |
| CHEMBL579200 | — | — | 1 | - |
| CHEMBL567169 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL565949 | — | EC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL576457 | — | EC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL567374 | — | EC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL568471 | — | EC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL579258 | — | EC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL568472 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL584678 | — | EC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL577042 | — | EC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL578578 | — | EC50 | = | 51000.0 | nM | 4.29 |
| CHEMBL568695 | — | EC50 | = | 56000.0 | nM | 4.25 |
| CHEMBL568243 | — | EC50 | = | 71000.0 | nM | 4.15 |
| CHEMBL583004 | — | EC50 | = | 71000.0 | nM | 4.15 |
| CHEMBL577470 | — | EC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL567582 | — | EC50 | = | 79000.0 | nM | 4.10 |
| CHEMBL567375 | — | EC50 | = | 83000.0 | nM | 4.08 |
| CHEMBL576658 | — | EC50 | = | 87000.0 | nM | 4.06 |
| CHEMBL568470 | — | EC50 | = | 91000.0 | nM | 4.04 |
| CHEMBL578594 | — | EC50 | = | 111000.0 | nM | - |
| CHEMBL568444 | — | EC50 | = | 773000.0 | nM | - |
| CHEMBL578588 | — | EC50 | = | 1290000.0 | nM | - |
| CHEMBL567376 | — | EC50 | = | 360000.0 | nM | - |
| CHEMBL578547 | — | EC50 | = | 529000.0 | nM | - |
| CHEMBL565362 | — | EC50 | = | 192000.0 | nM | - |
| CHEMBL572184 | — | EC50 | = | 364000.0 | nM | - |
| CHEMBL568456 | — | EC50 | = | 296000.0 | nM | - |
| CHEMBL565983 | — | EC50 | = | 200000.0 | nM | - |
| CHEMBL568242 | — | EC50 | = | 474000.0 | nM | - |
| CHEMBL583442 | — | EC50 | = | 688000.0 | nM | - |
| CHEMBL567169 | — | EC50 | = | 269000.0 | nM | - |
| CHEMBL579200 | — | EC50 | = | 407000.0 | nM | - |
| CHEMBL579199 | — | EC50 | = | 500000.0 | nM | - |
| CHEMBL578968 | — | EC50 | = | 692000.0 | nM | - |
| CHEMBL565361 | — | EC50 | = | 676000.0 | nM | - |
| CHEMBL577694 | — | EC50 | = | 308000.0 | nM | - |
| CHEMBL579016 | — | EC50 | = | 411000.0 | nM | - |
| CHEMBL585191 | — | EC50 | = | 550000.0 | nM | - |
| CHEMBL584886 | — | EC50 | = | 725000.0 | nM | - |
| CHEMBL565360 | — | EC50 | = | 214000.0 | nM | - |
| CHEMBL578579 | — | EC50 | = | 641000.0 | nM | - |
| CHEMBL584813 | — | EC50 | = | 793000.0 | nM | - |
| CHEMBL568438 | — | EC50 | = | 203000.0 | nM | - |