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Assay Detail

CHEMBL1048014

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Coxsackie virus A24 infected in human MRC5 cells assessed as reduction of virus induced cytopathic effect after 3 days by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Coxsackievirus A24
Cell Type MRC5
Confidence 1 — Organism
Curated By Autocuration

Target

Coxsackievirus A24 (CHEMBL612777)
Type ORGANISM
Organism Coxsackievirus A24

Publication

9-Arylpurines as a novel class of enterovirus inhibitors.
Aguado L, Thibaut HJ, Priego EM, Jimeno ML, Camarasa MJ, Neyts J, Pérez-Pérez MJ.
J Med Chem (2010) 53 : 316 -324
PubMed 19924996 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL571108 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL571108 EC50 = 2700.0 nM 5.57