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Assay Detail

CHEMBL1048098

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Binding
Inhibition of Clostridium welchii neuraminidase
26
Total Activities
13
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium perfringens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structural characteristics of flavanones and flavones from Cudrania tricuspidata for neuraminidase inhibition.
Ryu YB, Curtis-Long MJ, Lee JW, Ryu HW, Kim JY, Lee WS, Park KH.
Bioorg Med Chem Lett (2009) 19 : 4912 -4915
PubMed 19660948 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 5.15 6.42
Inhibition 13 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL218550 2 6.42
CHEMBL463145 NORARTOCARPETIN 2 5.95
CHEMBL220746 CUDRAFLAVANONE A 2 5.82
CHEMBL151 LUTEOLIN 2.0 2 5.34
CHEMBL221908 2 5.22
CHEMBL458395 2 5.09
CHEMBL221907 CUDRAFLAVONE B 2 4.99
CHEMBL218741 2 4.97
CHEMBL464825 MANGIFERIN 2 4.95
CHEMBL8996 ERIODICTYOL 2 4.80
CHEMBL28 APIGENIN 2 4.66
CHEMBL230558 CUDRAFLAVONE A 2 4.54
CHEMBL9352 NARINGENIN 2 4.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL218550 IC50 = 380.0 nM 6.42
CHEMBL463145 NORARTOCARPETIN IC50 = 1130.0 nM 5.95
CHEMBL220746 CUDRAFLAVANONE A IC50 = 1530.0 nM 5.82
CHEMBL151 LUTEOLIN IC50 = 4600.0 nM 5.34
CHEMBL221908 IC50 = 6010.0 nM 5.22
CHEMBL458395 IC50 = 8140.0 nM 5.09
CHEMBL221907 CUDRAFLAVONE B IC50 = 10140.0 nM 4.99
CHEMBL218741 IC50 = 10740.0 nM 4.97
CHEMBL464825 MANGIFERIN IC50 = 11200.0 nM 4.95
CHEMBL8996 ERIODICTYOL IC50 = 15970.0 nM 4.80
CHEMBL28 APIGENIN IC50 = 22110.0 nM 4.66
CHEMBL230558 CUDRAFLAVONE A IC50 = 29010.0 nM 4.54
CHEMBL9352 NARINGENIN IC50 = 57920.0 nM 4.24
CHEMBL151 LUTEOLIN Inhibition - % -
CHEMBL221907 CUDRAFLAVONE B Inhibition - % -
CHEMBL28 APIGENIN Inhibition - % -
CHEMBL221908 Inhibition - % -
CHEMBL8996 ERIODICTYOL Inhibition - % -
CHEMBL463145 NORARTOCARPETIN Inhibition - % -
CHEMBL9352 NARINGENIN Inhibition - % -
CHEMBL458395 Inhibition - % -
CHEMBL230558 CUDRAFLAVONE A Inhibition - % -
CHEMBL218741 Inhibition - % -
CHEMBL220746 CUDRAFLAVANONE A Inhibition - % -
CHEMBL218550 Inhibition - % -
CHEMBL464825 MANGIFERIN Inhibition - % -