Assay Detail

CHEMBL1048331

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Functional

Cytotoxicity against human 1A9 cells after 72 hrs by MTT assay

ChEMBL ↗

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Target

1A9 (CHEMBL614075) ↗

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Primary target 1A9

CHEMBL614075

Anchored from Assay target.

Protein identity 1A9

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	1A9
Confidence	1 — Organism
Curated By	Autocuration

Target

1A9 (CHEMBL614075) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Microtubule-stabilizing activity of zampanolide, a potent macrolide isolated from the Tongan marine sponge Cacospongia mycofijiensis.

Field JJ, Singh AJ, Kanakkanthara A, Halafihi T, Northcote PT, Miller JH.
J Med Chem (2009) 52 : 7328 -7332
PubMed 19877653 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.84	7.84

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL582439	ZAMPANOLIDE	—	1	7.84

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL582439	ZAMPANOLIDE	IC50	=	14.3	nM	7.84