Assay Detail
Functional
CHEMBL1052303
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HCV1b BK infected in human H2B2 cells expressing HEPREP 2b replicon by cell-ELISA assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | H2B2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559638 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559638 | — | EC50 | = | 11000.0 | nM | 4.96 |