Assay Detail
Binding
CHEMBL1052805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]Arg8-vasopressin from human vasopressin V2 receptor expressed in CHO-K1 cells by Packard Topcount scintillation counter
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Tetrahydroquinoline sulfonamides as vasopressin 1b receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.49 | 6.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL582857 | NELIVAPTAN | 2.0 | 1 | 6.49 |
| CHEMBL1204403 | — | — | 1 | - |
| CHEMBL1204126 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL582857 | NELIVAPTAN | Ki | = | 325.0 | nM | 6.49 |
| CHEMBL1204403 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1204126 | — | Ki | > | 10000.0 | nM | - |