Assay Detail
Binding
CHEMBL1053897
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Inhibition of rat diaphragm PDE5
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Diaphragm |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.89 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77651 | SOPHOFLAVESCENOL | — | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77651 | SOPHOFLAVESCENOL | IC50 | = | 13.0 | nM | 7.89 |