Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1055500

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MOLT4 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLT-4
Confidence 1 — Organism
Curated By Autocuration

Target

MOLT-4 (CHEMBL614177)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of tetrahydrotetramethylnaphthalene analogs as adult T-cell leukemia cell-selective proliferation inhibitors in a small chemical library constructed based on multi-template hypothesis.
Nakamura M, Hamasaki T, Tokitou M, Baba M, Hashimoto Y, Aoyama H.
Bioorg Med Chem (2009) 17 : 4740 -4746
PubMed 19443225 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.71 4.71

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL25202 TAMIBAROTENE 4.0 1 4.71

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL25202 TAMIBAROTENE IC50 = 19500.0 nM 4.71