Assay Detail
Binding
CHEMBL1059417
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.56 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL478857 | — | — | 1 | 5.70 |
| CHEMBL188999 | — | — | 1 | 5.66 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 5.50 |
| CHEMBL364123 | — | — | 1 | 5.48 |
| CHEMBL551792 | — | — | 1 | 5.46 |
| CHEMBL560847 | — | — | 1 | - |
| CHEMBL550235 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL478857 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL188999 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL107 | COLCHICINE | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL364123 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL551792 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL560847 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL550235 | — | IC50 | > | 10000.0 | nM | - |