Assay Detail
Binding
CHEMBL1062032
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDGFR
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Platelet-derived growth factor receptor (CHEMBL2095189) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.08 | 6.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL327127 | — | — | 1 | 6.86 |
| CHEMBL573820 | — | — | 1 | 6.33 |
| CHEMBL106772 | — | — | 1 | 6.20 |
| CHEMBL574059 | — | — | 1 | 5.90 |
| CHEMBL574058 | — | — | 1 | 5.84 |
| CHEMBL386051 | — | — | 1 | 5.78 |
| CHEMBL578006 | — | — | 1 | 5.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL327127 | — | IC50 | = | 139.0 | nM | 6.86 |
| CHEMBL573820 | — | IC50 | = | 463.0 | nM | 6.33 |
| CHEMBL106772 | — | IC50 | = | 636.0 | nM | 6.20 |
| CHEMBL574059 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL574058 | — | IC50 | = | 1430.0 | nM | 5.84 |
| CHEMBL386051 | — | IC50 | = | 1660.0 | nM | 5.78 |
| CHEMBL578006 | — | IC50 | = | 2340.0 | nM | 5.63 |