Assay Detail
Functional
CHEMBL1062089
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Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Bel-7402 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cucurbitane-type triterpenoids from the stems of Cucumis melo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.58 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | — | 1 | 8.10 |
| CHEMBL455518 | CUCURBITACIN A | — | 1 | 6.52 |
| CHEMBL540461 | 7BETA-HYDROXYCUCURBITACIN B | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507237 | CUCURBITACIN B | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL455518 | CUCURBITACIN A | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL540461 | 7BETA-HYDROXYCUCURBITACIN B | IC50 | = | 7590.0 | nM | 5.12 |