Assay Detail
Binding
CHEMBL1063785
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Inhibition of wild-type CK2 holoenzyme
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Zea mays |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.91 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92361 | — | — | 1 | 6.41 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | — | 1 | 6.30 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 6.07 |
| CHEMBL289277 | EMODIN | — | 1 | 6.05 |
| CHEMBL28 | APIGENIN | — | 1 | 5.92 |
| CHEMBL572880 | — | — | 1 | 5.79 |
| CHEMBL388978 | STAUROSPORINE | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92361 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL50 | QUERCETIN | IC50 | = | 850.0 | nM | 6.07 |
| CHEMBL289277 | EMODIN | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL28 | APIGENIN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL572880 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 14220.0 | nM | 4.85 |