Assay Detail
Functional
CHEMBL1065323
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Antiproliferative activity against human Caco-2 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Caco-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of novel taspine derivatives as antiangiogenic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.14 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595922 | — | — | 1 | 7.28 |
| CHEMBL470867 | TASPINE | — | 1 | 6.82 |
| CHEMBL595691 | — | — | 1 | 5.51 |
| CHEMBL593123 | — | — | 1 | 4.96 |
| CHEMBL593143 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595922 | — | IC50 | = | 52.5 | nM | 7.28 |
| CHEMBL470867 | TASPINE | IC50 | = | 153.0 | nM | 6.82 |
| CHEMBL595691 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL593123 | — | IC50 | = | 11003.0 | nM | 4.96 |
| CHEMBL593143 | — | IC50 | - | — | - |