Assay Detail
Binding
CHEMBL1065462
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]granisectron from 5HT3 receptor in Wistar rat forebrain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
5-hydroxytryptamine receptor 3A (CHEMBL2411) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.62 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3084708 | — | — | 1 | 7.75 |
| CHEMBL3084712 | — | — | 1 | 7.60 |
| CHEMBL3084706 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3084708 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL3084712 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL3084706 | — | IC50 | = | 32.0 | nM | 7.50 |