Assay Detail
Binding
CHEMBL1065675
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human NTPdase1 by capillary electrophoresis method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ectonucleoside triphosphate diphosphohydrolase 1 (CHEMBL5722) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.28 | 5.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL608559 | — | — | 1 | 5.59 |
| CHEMBL496030 | — | — | 1 | 4.97 |
| CHEMBL590956 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL608559 | — | Ki | = | 2590.0 | nM | 5.59 |
| CHEMBL496030 | — | Ki | = | 10700.0 | nM | 4.97 |
| CHEMBL590956 | — | Ki | > | 40000.0 | nM | - |