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Assay Detail

CHEMBL1065678

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat NTPdase3 by capillary electrophoresis method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Nucleoside triphosphate diphosphohydrolase 3 (CHEMBL1075237)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold.
Baqi Y, Lee SY, Iqbal J, Ripphausen P, Lehr A, Scheiff AB, Zimmermann H, Bajorath J, Müller CE.
J Med Chem (2010) 53 : 2076 -2086
PubMed 20146483 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 5.54 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL223344 RB 2 1 5.96
CHEMBL498423 1 5.82
CHEMBL256057 ACID BLUE 25 1 4.84
CHEMBL496030 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL223344 RB 2 Ki = 1100.0 nM 5.96
CHEMBL498423 Ki = 1500.0 nM 5.82
CHEMBL256057 ACID BLUE 25 Ki = 14300.0 nM 4.84
CHEMBL496030 Ki - -