Assay Detail
Binding
CHEMBL1066258
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human rheumatoid synovial fibroblasts gelatinase A after 30 mins by fluorescence plate reader
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.06 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL592228 | — | — | 1 | 6.40 |
| CHEMBL790 | CHLORHEXIDINE | 4.0 | 1 | 5.12 |
| CHEMBL592329 | — | — | 1 | 4.91 |
| CHEMBL290632 | PROCYANIDIN C1 | — | 1 | 4.50 |
| CHEMBL592373 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL592228 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL790 | CHLORHEXIDINE | IC50 | = | 7630.0 | nM | 5.12 |
| CHEMBL592329 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL290632 | PROCYANIDIN C1 | IC50 | = | 31400.0 | nM | 4.50 |
| CHEMBL592373 | — | IC50 | = | 43200.0 | nM | 4.37 |