Assay Detail
Physicochemical
CHEMBL1066867
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Octanol-water partition coefficient, log P of the compound
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel semisynthetic spin-labeled derivatives of podophyllotoxin with cytotoxic and antioxidative activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.76 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL592178 | — | — | 1 | 7.00 |
| CHEMBL592354 | — | — | 1 | 6.96 |
| CHEMBL592321 | — | — | 1 | 6.92 |
| CHEMBL592396 | — | — | 1 | 6.82 |
| CHEMBL578298 | — | — | 1 | 6.79 |
| CHEMBL592397 | — | — | 1 | 6.74 |
| CHEMBL592174 | — | — | 1 | 6.68 |
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL592178 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL592354 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL592321 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL592396 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL578298 | — | IC50 | = | 161.0 | nM | 6.79 |
| CHEMBL592397 | — | IC50 | = | 183.0 | nM | 6.74 |
| CHEMBL592174 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 680.0 | nM | 6.17 |