Assay Detail
Binding
CHEMBL1067149
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Inhibition of CDC2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Semi-synthetic aristolactams--inhibitors of CDK2 enzyme.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.69 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388956 | ARISTOLACTAM AIIIA | — | 1 | 6.70 |
| CHEMBL603097 | — | — | 1 | 6.70 |
| CHEMBL609040 | — | — | 1 | 6.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388956 | ARISTOLACTAM AIIIA | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL603097 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL609040 | — | IC50 | = | 214.0 | nM | 6.67 |