Assay Detail
Binding
CHEMBL1067221
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Inhibition of Dengue virus type 2 NS5 RNA methyltransferase at 80 nM enzyme concentration
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening on a desktop computer grid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.07 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL115145 | — | — | 1 | 5.15 |
| CHEMBL597979 | — | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL115145 | — | IC50 | = | 7140.0 | nM | 5.15 |
| CHEMBL597979 | — | IC50 | = | 10240.0 | nM | 4.99 |