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Assay Detail

CHEMBL1067702

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Functional
Induction of insulin secretion in isolated rat pancreas
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Pancreas
Confidence 1 — Organism
Curated By Autocuration

Target

Pancreas (CHEMBL613650)
Type TISSUE
Organism Rattus norvegicus

Publication

A novel insulin secretagogue based on a dinucleoside polyphosphate scaffold.
Eliahu S, Barr HM, Camden J, Weisman GA, Fischer B.
J Med Chem (2010) 53 : 2472 -2481
PubMed 20175517 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.55 7.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2309024 1 7.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2309024 EC50 = 28.0 nM 7.55