Assay Detail
Functional
CHEMBL1068615
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Antimalarial activity against chloroquine and pyrimethamine-resistant Plasmodium falciparum K1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.08 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL295759 | — | — | 1 | 5.29 |
| CHEMBL596332 | NORMELINONINE F HYDROCHLORIDE | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL295759 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL596332 | NORMELINONINE F HYDROCHLORIDE | IC50 | = | 13600.0 | nM | 4.87 |