Assay Detail
Binding
CHEMBL1068633
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Inhibition of Bacillus anthracis sortase A by FRET-based enzyme kinetics assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus anthracis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.14 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL608382 | — | — | 1 | 6.52 |
| CHEMBL608987 | — | — | 1 | 6.40 |
| CHEMBL604473 | — | — | 1 | 5.85 |
| CHEMBL594500 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL608382 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL608987 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL604473 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL594500 | — | Ki | = | 1700.0 | nM | 5.77 |