Assay Detail
Binding
CHEMBL1069757
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to granulocyte colony stimulating factor receptor by SPR biosensor technique
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Granulocyte colony-stimulating factor receptor (CHEMBL1996) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Molecular design of small organic molecules based on structural information for a conformationally constrained peptide that binds to G-CSF receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 4.52 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL602139 | — | — | 1 | 4.70 |
| CHEMBL590814 | — | — | 1 | 4.33 |
| CHEMBL590815 | — | — | 1 | - |
| CHEMBL589173 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL602139 | — | Kd | = | 20000.0 | nM | 4.70 |
| CHEMBL590814 | — | Kd | = | 47000.0 | nM | 4.33 |
| CHEMBL590815 | — | Kd | - | — | - | |
| CHEMBL589173 | — | Kd | - | — | - |