Assay Detail
Binding
CHEMBL1070003
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Inhibition of Plasmodium falciparum recombinant falcipain-3 by microtiter plate spectrofluorimetry
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antimalarial activity of azadipeptide nitriles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.76 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL594719 | — | — | 1 | 6.96 |
| CHEMBL604079 | — | — | 1 | 6.52 |
| CHEMBL604078 | — | — | 1 | 5.80 |
| CHEMBL608115 | — | — | 1 | 5.72 |
| CHEMBL595637 | — | — | 1 | 4.80 |
| CHEMBL604281 | — | — | 1 | 4.75 |
| CHEMBL603537 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL594719 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL604079 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL604078 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL608115 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL595637 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL604281 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL603537 | — | IC50 | > | 50000.0 | nM | - |