Assay Detail
Binding
CHEMBL1070724
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human P2Y12 receptor expressed in CHO cells in presence of 0.4% human serum albumin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Part II: piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.19 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL601906 | — | — | 1 | 8.20 |
| CHEMBL601907 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL601906 | — | Ki | = | 6.3 | nM | 8.20 |
| CHEMBL601907 | — | Ki | = | 6.7 | nM | 8.17 |