Assay Detail
Binding
CHEMBL1071607
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Inhibition of human monoamine oxidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.66 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487601 | JACEOSIDINE | — | 1 | 4.72 |
| CHEMBL172350 | EUPAFOLIN | — | 1 | 4.60 |
| CHEMBL66 | (+)-TAXIFOLIN | — | 1 | - |
| CHEMBL9323 | DIHYDROKAEMPFEROL | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487601 | JACEOSIDINE | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL172350 | EUPAFOLIN | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL66 | (+)-TAXIFOLIN | IC50 | = | 154700.0 | nM | - |
| CHEMBL9323 | DIHYDROKAEMPFEROL | IC50 | = | 153100.0 | nM | - |