Assay Detail
Binding
CHEMBL1072134
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of amyloid beta (1-40) fibril formation by thioflavin T formation assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 4 | - | - |
| IC50 | 1 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1142 | 4-AMINOPHENOL | — | 1 | 4.05 |
| CHEMBL610796 | — | — | 1 | - |
| CHEMBL597994 | — | — | 1 | - |
| CHEMBL597993 | — | — | 1 | - |
| CHEMBL590603 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1142 | 4-AMINOPHENOL | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL610796 | — | Inhibition | - | % | - | |
| CHEMBL597994 | — | Inhibition | - | % | - | |
| CHEMBL597993 | — | Inhibition | - | % | - | |
| CHEMBL590603 | — | Inhibition | - | % | - |