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Assay Detail

CHEMBL1073148

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MAPK
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

New potential antitumor compounds from the plant Aristolochia manshuriensis as inhibitors of the CDK2 enzyme.
Hegde VR, Borges S, Patel M, Das PR, Wu B, Gullo VP, Chan TM.
Bioorg Med Chem Lett (2010) 20 : 1344 -1346
PubMed 20097074 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.45 4.45

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388956 ARISTOLACTAM AIIIA 1 4.45

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388956 ARISTOLACTAM AIIIA IC50 = 35335.0 nM 4.45