Assay Detail
Binding
CHEMBL1073715
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Inhibition of HIV1 reverse transcriptase by EIA
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 reverse transcriptase (CHEMBL247) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Biomimetic synthesis and anti-HIV activity of dimeric phloroglucinols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 6.92 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57 | NEVIRAPINE | 4.0 | 1 | 8.44 |
| CHEMBL609163 | — | — | 1 | 6.33 |
| CHEMBL578267 | — | — | 1 | 5.99 |
| CHEMBL597564 | — | — | 1 | - |
| CHEMBL577877 | — | — | 1 | - |
| CHEMBL601240 | — | — | 1 | - |
| CHEMBL603489 | — | — | 1 | - |
| CHEMBL591220 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57 | NEVIRAPINE | EC50 | = | 3.6 | nM | 8.44 |
| CHEMBL609163 | — | EC50 | = | 470.0 | nM | 6.33 |
| CHEMBL578267 | — | EC50 | = | 1035.0 | nM | 5.99 |
| CHEMBL597564 | — | EC50 | - | — | - | |
| CHEMBL577877 | — | EC50 | - | — | - | |
| CHEMBL601240 | — | EC50 | - | — | - | |
| CHEMBL603489 | — | EC50 | - | — | - | |
| CHEMBL591220 | — | EC50 | - | — | - |