Assay Detail
Binding
CHEMBL1074339
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DADLE from delta opioid receptor expressed in CHO cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.65 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL72180 | — | — | 1 | 7.12 |
| CHEMBL592300 | — | — | 1 | 5.65 |
| CHEMBL589260 | — | — | 1 | 5.21 |
| CHEMBL599175 | — | — | 1 | 5.14 |
| CHEMBL599174 | — | — | 1 | 5.13 |
| CHEMBL592301 | — | — | 1 | - |
| CHEMBL592302 | — | — | 1 | - |
| CHEMBL598977 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL72180 | — | Ki | = | 75.0 | nM | 7.12 |
| CHEMBL592300 | — | Ki | = | 2260.0 | nM | 5.65 |
| CHEMBL589260 | — | Ki | = | 6150.0 | nM | 5.21 |
| CHEMBL599175 | — | Ki | = | 7210.0 | nM | 5.14 |
| CHEMBL599174 | — | Ki | = | 7480.0 | nM | 5.13 |
| CHEMBL592301 | — | Ki | > | 4500.0 | nM | - |
| CHEMBL592302 | — | Ki | > | 4500.0 | nM | - |
| CHEMBL598977 | — | Ki | > | 4300.0 | nM | - |