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Assay Detail

CHEMBL1100249

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Klebsiella pneumoniae ATCC 700603 after 24 hrs by broth microdilution method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Klebsiella pneumoniae
Confidence 1 — Organism
Curated By Autocuration

Target

Klebsiella pneumoniae (CHEMBL350)
Type ORGANISM
Organism Klebsiella pneumoniae

Publication

Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines.
Rudys S, Ríos-Luci C, Pérez-Roth E, Cikotiene I, Padrón JM.
Bioorg Med Chem Lett (2010) 20 : 1504 -1506
PubMed 20144871 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.25 4.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1081640 1 4.25
CHEMBL1081475 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1081640 IC50 = 56000.0 nM 4.25
CHEMBL1081475 IC50 > 100000.0 nM -