Assay Detail
Binding
CHEMBL1100506
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Trypanosoma cruzi X10/1 recombinant trypanothione reductase assessed as increase in absorbance at 410 nm due to the formation of TNB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.46 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1098695 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1098695 | — | EC50 | = | 35000.0 | nM | 4.46 |