Assay Detail
Binding
CHEMBL1101466
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Displacement of [33P]-S1P1 from human S1P1 receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
S1P receptor mediated activity of FTY720 phosphate mimics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.22 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190006 | — | — | 1 | 9.80 |
| CHEMBL325050 | — | — | 1 | 6.15 |
| CHEMBL326346 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190006 | — | IC50 | = | 0.16 | nM | 9.80 |
| CHEMBL325050 | — | IC50 | = | 710.0 | nM | 6.15 |
| CHEMBL326346 | — | IC50 | = | 1900.0 | nM | 5.72 |