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Assay Detail

CHEMBL1101617

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of XOD
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL1929)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemical constituents from the aerial parts of Artemisia minor.
He ZZ, Yan JF, Song ZJ, Ye F, Liao X, Peng SL, Ding LS.
J Nat Prod (2009) 72 : 1198 -1201
PubMed 19476336 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.60 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1467 ALLOPURINOL 4.0 1 6.75
CHEMBL1085430 ARTEMINORIN C 1 5.11
CHEMBL151 LUTEOLIN 2.0 1 4.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1467 ALLOPURINOL IC50 = 180.0 nM 6.75
CHEMBL1085430 ARTEMINORIN C IC50 = 7710.0 nM 5.11
CHEMBL151 LUTEOLIN IC50 = 11540.0 nM 4.94