Assay Detail
Binding
CHEMBL1102016
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human SST2 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.12 | 5.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1076623 | — | — | 1 | 5.45 |
| CHEMBL1076624 | — | — | 1 | 5.34 |
| CHEMBL1076622 | — | — | 1 | 5.26 |
| CHEMBL1076625 | — | — | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1076623 | — | Kd | = | 3548.13 | nM | 5.45 |
| CHEMBL1076624 | — | Kd | = | 4570.88 | nM | 5.34 |
| CHEMBL1076622 | — | Kd | = | 5495.41 | nM | 5.26 |
| CHEMBL1076625 | — | Kd | = | 38018.94 | nM | 4.42 |