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Assay Detail

CHEMBL1102023

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to 5HT2C receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2C (CHEMBL225)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Decahydroisoquinoline derivatives as novel non-peptidic, potent and subtype-selective somatostatin sst(3) receptor antagonists.
Troxler T, Hurth K, Schuh KH, Schoeffter P, Langenegger D, Enz A, Hoyer D.
Bioorg Med Chem Lett (2010) 20 : 1728 -1734
PubMed 20137944 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.37 6.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1076624 1 6.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1076624 Kd = 426.58 nM 6.37