Assay Detail
Binding
CHEMBL1102104
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FLT3
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein kinase FLT3 (CHEMBL1974) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.87 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1080902 | — | — | 1 | 7.18 |
| CHEMBL1076721 | — | — | 1 | 6.89 |
| CHEMBL1086736 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1080902 | — | Ki | = | 66.0 | nM | 7.18 |
| CHEMBL1076721 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL1086736 | — | Ki | = | 290.0 | nM | 6.54 |