Assay Detail
Binding
CHEMBL1102109
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Inhibition of KDR
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.74 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1086736 | — | — | 1 | 6.00 |
| CHEMBL1080902 | — | — | 1 | 5.75 |
| CHEMBL1076721 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1086736 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL1080902 | — | Ki | = | 1800.0 | nM | 5.75 |
| CHEMBL1076721 | — | Ki | = | 3400.0 | nM | 5.47 |