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Assay Detail

CHEMBL1102422

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from IFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Fatty acid-binding protein, intestinal (CHEMBL4879)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.
Hertzel AV, Hellberg K, Reynolds JM, Kruse AC, Juhlmann BE, Smith AJ, Sanders MA, Ohlendorf DH, Suttles J, Bernlohr DA.
J Med Chem (2009) 52 : 6024 -6031
PubMed 19754198 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.18 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1077990 1 5.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1077990 Ki = 6570.0 nM 5.18