Assay Detail
Binding
CHEMBL1102723
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Inhibition of chymotrypsin-like activity of 20S proteasome
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.37 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1076555 | — | — | 1 | 6.37 |
| CHEMBL562493 | — | — | 1 | 6.37 |
| CHEMBL1081262 | — | — | 1 | 6.37 |
| CHEMBL579212 | — | — | 1 | 6.37 |
| CHEMBL1081626 | — | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1076555 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL562493 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL1081262 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL579212 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL1081626 | — | IC50 | = | 430.0 | nM | 6.37 |