Assay Detail
Functional
CHEMBL1102811
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Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoprenylated chromone derivatives from the plant endophytic fungus Pestalotiopsis fici.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.79 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.82 |
| CHEMBL1078132 | PESTALOFICIOL L | — | 1 | 4.76 |
| CHEMBL1078031 | PESTALOFICIOL F | — | 1 | - |
| CHEMBL1079364 | PESTALOFICIOL G/H | — | 1 | - |
| CHEMBL1080257 | PESTALOFICIOL I | — | 1 | - |
| CHEMBL1080258 | PESTALOFICIOL J | — | 1 | - |
| CHEMBL1081525 | PESTALOFICIOL K | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1078132 | PESTALOFICIOL L | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL1078031 | PESTALOFICIOL F | IC50 | > | 143900.0 | nM | - |
| CHEMBL1079364 | PESTALOFICIOL G/H | IC50 | > | 143900.0 | nM | - |
| CHEMBL1080257 | PESTALOFICIOL I | IC50 | = | 136100.0 | nM | - |
| CHEMBL1080258 | PESTALOFICIOL J | IC50 | > | 153800.0 | nM | - |
| CHEMBL1081525 | PESTALOFICIOL K | IC50 | > | 132500.0 | nM | - |