Assay Detail
Binding
CHEMBL1103263
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Binding affinity to fluorescein-labeled HIV1 single-stranded RNA of packaging element psi by titration method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Identification of specific small molecule ligands for stem loop 3 ribonucleic acid of the packaging signal Psi of human immunodeficiency virus-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.42 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL458765 | — | — | 1 | 5.64 |
| CHEMBL463783 | — | — | 1 | 5.52 |
| CHEMBL1078817 | — | — | 1 | 5.11 |
| CHEMBL299564 | — | — | 1 | - |
| CHEMBL1077994 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL458765 | — | Kd | = | 2300.0 | nM | 5.64 |
| CHEMBL463783 | — | Kd | = | 3000.0 | nM | 5.52 |
| CHEMBL1078817 | — | Kd | = | 7800.0 | nM | 5.11 |
| CHEMBL299564 | — | Kd | > | 4900000.0 | nM | - |
| CHEMBL1077994 | — | Kd | = | 276000.0 | nM | - |