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Assay Detail

CHEMBL1103660

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to amyloid beta (1 to 42) aggregates after 2 hrs by saturation binding method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for beta-amyloid plaques in Alzheimer's disease.
Cui MC, Li ZJ, Tang RK, Liu BL.
Bioorg Med Chem (2010) 18 : 2777 -2784
PubMed 20211565 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.89 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1092857 1 9.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1092857 Ki = 0.13 nM 9.89