Assay Detail
Binding
CHEMBL1104176
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]-IP10 from rhesus monkey CXCR3 expressed in human PBMC after 2 hrs in RPMI buffer by scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca mulatta |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Optimization of a series of quinazolinone-derived antagonists of CXCR3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1077831 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1077831 | — | IC50 | = | 2.0 | nM | 8.70 |