Assay Detail
Functional
CHEMBL1104489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antileishmanial activity against Leishmania braziliensis MHOM/PE/PER006 promastigote infected BALB/c mouse macrophages after 48 hrs by Giemsa staining method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania braziliensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.58 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | 7.00 |
| CHEMBL1090250 | — | — | 1 | 6.22 |
| CHEMBL1093995 | — | — | 1 | 4.98 |
| CHEMBL1090368 | — | — | 1 | 4.96 |
| CHEMBL1090595 | — | — | 1 | 4.76 |
| CHEMBL1090597 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1090250 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL1093995 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL1090368 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL1090595 | — | IC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL1090597 | — | IC50 | > | 2000.0 | nM | - |