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Assay Detail

CHEMBL1105669

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against african green monkey Vero cells by green fluorescent protein based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Chlorocebus sabaeus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Vero (CHEMBL391)
Type CELL-LINE
Organism Chlorocebus sabaeus

Publication

Cytotoxicity against KB and NCI-H187 cell lines of modified flavonoids from Kaempferia parviflora.
Yenjai C, Wanich S.
Bioorg Med Chem Lett (2010) 20 : 2821 -2823
PubMed 20362442 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.20 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL123 ELLIPTECINE 1 5.64
CHEMBL1098028 1 5.57
CHEMBL1087979 1 4.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL123 ELLIPTECINE IC50 = 2290.0 nM 5.64
CHEMBL1098028 IC50 = 2670.0 nM 5.57
CHEMBL1087979 IC50 = 41200.0 nM 4.38