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Assay Detail

CHEMBL1107360

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Tetracenoquinocin and 5-iminoaranciamycin from a sponge-derived Streptomyces sp. Sp080513GE-26.
Motohashi K, Takagi M, Shin-Ya K.
J Nat Prod (2010) 73 : 755 -758
PubMed 20192240 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1096602 ARANCIAMYCIN 1 5.57
CHEMBL1096258 1 -
CHEMBL1094937 TETRACENOQUINOCIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1096602 ARANCIAMYCIN IC50 = 2700.0 nM 5.57
CHEMBL1096258 IC50 > 200000.0 nM -
CHEMBL1094937 TETRACENOQUINOCIN IC50 = 120000.0 nM -